U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 6781 - 6790 of 7099 results

Status:
Investigational
Source:
NCT02726269: Phase 3 Helicobacter Pylori Gastritis
(2012)
Source URL:

Class:
POLYMER

Status:
Investigational
Source:
NCT00543400: Phase 2 Percutaneous Coronary Intervention (PCI)
(2007)
Source URL:

Class:
POLYMER

Status:
Investigational
Source:
NCT00003467: Phase 2 Brain and Central Nervous System Tumors
(1998)
Source URL:

Class:
POLYMER

Status:
Investigational
Source:
NCT03009799: Phase 2 Adenoviral Conjunctivitis
(2017)
Source URL:

Class:
POLYMER

Status:
Investigational
Source:
BAN:COPOVITHANE [BAN]
Source URL:

Class:
POLYMER

Status:
Investigational
Source:
INN:carbetimer
Source URL:

Class:
POLYMER

Carbetimer is a low molecular weight polymer derived from ethylene and maleic anhydride with potent antineoplastic activity. Preclinical studies have shown antitumor effects against many tumor cell lines including B 16 melanoma. Its antitumor actions are felt to include both reduction of uridine and cytidine nucleoside triphosphate as well as the diminution of pyrimidine salvage by inhibiting uridine, cytidine, and thymidine kinase. Besides direct antiproliferative effects, Carbetimer could act through immunomodulation, as suggested by the induction of cytotoxic T-cells in mice and the discordant in vitro and in vivo activities against the Lewis lung carcinoma model. Unfortunately, Carbetimer failed to demonstrate efficacy in Phase II trials
Status:
Investigational
Source:
USAN:SODIUM AMYLOSULFATE [USAN]
Source URL:

Class:
POLYMER

Status:
Investigational
Source:
INN:surfomer
Source URL:

Class:
POLYMER

Surfomer (also known as alpha-olefin maleic acid) is a copolymer of maleic acid and alpha-olefin useful for control of whole-body cholesterol homeostasis. Surfomer reduces intestinal cholesterol absorption by decreasing membrane hydrophobicity at microvillus level thereby impairing the interaction with intestinal cholesterol of both exogenous and endogenous origin. In the hamsters, Surfomer was shown to effectively reduce intestinal cholesterol absorption in a dose-dependent manner, to increase hepatic and intestinal cholesterol synthesis and to decrease plasma total and LDL-cholesterol.
Status:
Investigational
Source:
USAN:Anoxomer
Source URL:

Class:
POLYMER

Anoxomer (E323) is a food additive. It was designed to allow the introduction of established antioxidants in a non-absorbable manner in order to avoid potential health risk associated with their digestion. Anoxomer is an antioxidant, it protects food from deterioration caused by oxidation. Anoxomer may be safely used as an antioxidant in food at a level of not more than 5,000 parts per million based on fat and oil content of the food.
Status:
Investigational
Source:
USAN:POLYDEXTROSE [USAN]
Source URL:

Class:
POLYMER

Showing 6781 - 6790 of 7099 results