U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 49 - 64 of 7004 results

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Description

Talopram (Lu 3-010) is a selective inhibitor norepinephrine transporter belonging to the antidepressants of the thymoleptic group.
Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (MIXED)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ABSOLUTE)

Targets:


Description

Khelloside is a component of Ammi visnaga L. fruits extract, a medicine which is used in Egypt as remedy for the treatment of kidney stones. Khelloside itself exhibits a wide variety of biological activities including anti-anginal, antiatherosclerotic, lipid altering, antipyretic and spasmolytic. It was clinically tested for asthma, angina pectoris and skin disease, however its develoment seems to be discontinued.
Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Description

Carnosine is a dipeptide composed of the amino acids beta-histidine and l-alanine. It is widely present in muscle and brain tissues. It possesses strong and specific antioxidant properties, protects against radiation damage, and promotes wound healing. The antioxidant mechanism of carnosine is attributed to its chelating effect against metal ions, superoxide dismutase (SOD)-like activity, ROS and free radicals scavenging ability. In addition, was shown, that carnosine significantly protects against TCA-induced liver carcinogenesis in rats, through its antioxidant, antinutritive, and anti-inflammatory effects, and induction of apoptosis. It also may be a therapeutic agent against Parkinson's disease. Experiments on animal have shown the sepsis healing therapeutic potential of carnosine.
Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ABSOLUTE)

PRORENOATE POTASSIUM

MORE DETAILS...
Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ABSOLUTE)