BCR-ABL KINASE T315I MUTANT (IMATINIB RESISTANT)

Substance Class	Protein Created by `admin` on `Tue Oct 22 00:57:08 UTC 2019` Edited by `admin` on `Tue Oct 22 00:57:08 UTC 2019`
Protein Sub Type
Sequence Type	REPRESENTIVE
Record UNII	WF082S23P7
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

Common Name

English

BCR-ABL KINASE T315I MUTANT

Common Name

English

Related Record Type Details


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Comments:

NRC-AN-019 treatments were able to reduce leukemia symptoms significantly in both Baf3Wt and Baf3 (T315I) imatinib resistant leukemic mice.


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Comments:

nonphosphorylated form

Qualification:

Kd

Amount:


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INHIBITOR->RESISTANT TARGET


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INHIBITOR -> TARGET


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INHIBITOR->RESISTANT TARGET

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL