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Details

Stereochemistry ACHIRAL
Molecular Formula C12H14N2.2ClH
Molecular Weight 259.175
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N-(1-NAPHTHYL)ETHYLENEDIAMINE DIHYDROCHLORIDE

SMILES

Cl.Cl.NCCNC1=C2C=CC=CC2=CC=C1

InChI

InChIKey=MZNYWPRCVDMOJG-UHFFFAOYSA-N
InChI=1S/C12H14N2.2ClH/c13-8-9-14-12-7-3-5-10-4-1-2-6-11(10)12;;/h1-7,14H,8-9,13H2;2*1H

HIDE SMILES / InChI

Molecular Formula C12H14N2
Molecular Weight 186.253
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
58.0 nM [Ki]
61.0 nM [Ki]
48.0 nM [Ki]
PubMed

PubMed

TitleDatePubMed
Determination of nitrite by sequential injection analysis of electrokinetic flow analysis system.
2002 Mar 11
The application of the chromatomembrane cell for the absorptive sampling of nitrogen dioxide followed by continuous determination of nitrite using a micro-flow injection system.
2002 May 16
Flow-injection simultaneous determination of selenium(IV) and selenium(IV + VI) using photooxidative coupling of p-hydrazinobensenesulfonic acid with N-(1-naphthyl)ethylenediamine.
2004 Dec 15
Determination of mimosine by a sensitive indirect spectrophotometric method.
2004 Jun 17
Abstracts of papers presented at the 2008 pittsburgh conference.
2008
Pro- and anti-inflammatory cytokines release in mice injected with Crotalus durissus terrificus venom.
2008
Ameliorative role of Atorvastatin and Pitavastatin in L-Methionine induced vascular dementia in rats.
2008 Aug 9
Antioxidant and free radical scavenging activity of Spondias pinnata.
2008 Dec 9
A rapid technique for determination of nitrate and nitric acid by acid reduction and diazotization at elevated temperature.
2008 Jul 14
Leukotriene B4-loaded microspheres: a new therapeutic strategy to modulate cell activation.
2008 Jul 15
Natriuretic peptides modify Pseudomonas fluorescens cytotoxicity by regulating cyclic nucleotides and modifying LPS structure.
2008 Jul 9
Modification of AOAC method 973.31 for determination of nitrite in cured meats.
2008 Jul-Aug
Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes in vitro.
2008 Jun 13
Role of vitamins C and e in regulating antioxidant and pro-oxidant markers in preeclampsia.
2008 Nov
Enhanced production of nitric oxide, reactive oxygen species, and pro-inflammatory cytokines in very long chain saturated fatty acid-accumulated macrophages.
2008 Nov 28
Nitric oxide production in the exhaled air of patients with pulmonary tuberculosis in relation to HIV co-infection.
2008 Oct 24
Development and validation of spectrophotometric methods for determination of ceftazidime in pharmaceutical dosage forms.
2008 Sep
The inhibitory effect of quercitrin gallate on iNOS expression induced by lipopolysaccharide in Balb/c mice.
2008 Sep
Anti-inflammatory effects of Radix Gentianae Macrophyllae (Qinjiao), Rhizoma Coptidis (Huanglian) and Citri Unshiu Pericarpium (Wenzhou migan) in animal models.
2008 Sep 2
Development of a selective and sensitive spectrophotometric method for the trace determination of thallium(III) using 3-methyl-2-benzothiazolinone hydrazone hydrochloride and N-(1-naphthyl)-ethylenediamine dihydrochloride.
2008 Sep-Oct
Digestive proteolytic activity in the Sunn pest, Eurygaster integriceps.
2009
Nitric oxide production by the human intestinal microbiota by dissimilatory nitrate reduction to ammonium.
2009
Purification and characterization of a lectin from Phaseolus vulgaris cv. (Anasazi beans).
2009
Alternative spectrofluorimetric determination of short-chain volatile fatty acids in aqueous samples.
2009 Apr 15
Pro-inflammatory and oxidative stress pathways which compromise sperm motility and survival may be altered by L-carnitine.
2009 Apr-Jun
Activation of the steroid and xenobiotic receptor, SXR, induces apoptosis in breast cancer cells.
2009 Jan 5
Acute seizure activity promotes lipid peroxidation, increased nitrite levels and adaptive pathways against oxidative stress in the frontal cortex and striatum.
2009 Jul-Aug
Crocetin reduces TNBS-induced experimental colitis in mice by downregulation of NFkB.
2009 Jul-Sep
Cordycepin Suppresses Expression of Diabetes Regulating Genes by Inhibition of Lipopolysaccharide-induced Inflammation in Macrophages.
2009 Jun
[Determination of the daily changes curve of nitrogen oxides in the atmosphere by digital imaging colorimetry method].
2009 Jun
Effects of L-NAME, a non-specific nitric oxide synthase inhibitor, on AlCl3-induced toxicity in the rat forebrain cortex.
2009 Mar
Anti-inflammatory effects of the gorgonian Pseudopterogorgia elisabethae collected at the Islands of Providencia and San Andrés (SW Caribbean).
2009 Mar 10
Antiulcer activity of fluvoxamine in rats and its effect on oxidant and antioxidant parameters in stomach tissue.
2009 May 20
Sources of variation for indoor nitrogen dioxide in rural residences of Ethiopia.
2009 Nov 18
In vitro antioxidant and antihyperlipidemic activities of Bauhinia variegata Linn.
2009 Oct
Spectrophotometric method for the determination of chromium (VI) in water samples.
2009 Oct
Pichinde virus induces microvascular endothelial cell permeability through the production of nitric oxide.
2009 Oct 8
Acacia Senegal gum exudate offers protection against cyclophosphamide-induced urinary bladder cytotoxicity.
2009 Sep-Oct
Suppression of inflammatory mediators by cruciferous vegetable-derived indole-3-carbinol and phenylethyl isothiocyanate in lipopolysaccharide-activated macrophages.
2010
Development and validation of spectrophotometric methods for estimating amisulpride in pharmaceutical preparations.
2010
Acanthopanax koreanum fruit waste inhibits lipopolysaccharide-induced production of nitric oxide and prostaglandin E2 in RAW 264.7 macrophages.
2010
Immunostimulatory Effects of Cordyceps militaris on Macrophages through the Enhanced Production of Cytokines via the Activation of NF-kappaB.
2010 Apr
Inhibition of inducible nitric oxide synthase prevents mitochondrial damage and improves survival of steatotic partial liver grafts.
2010 Feb 15
Vaccination of mice with salmonella expressing VapA: mucosal and systemic Th1 responses provide protection against Rhodococcus equi infection.
2010 Jan 13
The Ca2+ activated SK3 channel is expressed in microglia in the rat striatum and contributes to microglia-mediated neurotoxicity in vitro.
2010 Jan 14
Tetrahydroabietic Acid, a Reduced Abietic Acid, Inhibits the Production of Inflammatory Mediators in RAW264.7 Macrophages Activated with Lipopolysaccharide.
2010 Mar
Inhibitory Potencies of Several Iridoids on Cyclooxygenase-1, Cyclooxygnase-2 Enzymes Activities, Tumor Necrosis factor-α and Nitric Oxide Production In Vitro.
2010 Mar
On-line analysis of volatile fatty acids in anaerobic treatment processes.
2010 May 23
EGb761 protects motoneurons against avulsion-induced oxidative stress in rats.
2010 May 24
Effect of St. John's Wort (Hypericum perforatum) treatment on restraint stress-induced behavioral and biochemical alteration in mice.
2010 May 7
Patents

Patents

Substance Class Chemical
Created
by admin
on Tue Oct 22 13:36:11 UTC 2019
Edited
by admin
on Tue Oct 22 13:36:11 UTC 2019
Record UNII
H734599KJL
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
N-(1-NAPHTHYL)ETHYLENEDIAMINE DIHYDROCHLORIDE
MI  
Systematic Name English
REAGENTS, BRATTON-MARSHALL
Brand Name English
N-(1-NAPHTHYL)ETHYLENEDIAMINE DIHYDROCHLORIDE [MI]
Common Name English
N-(1-NAPTHYL)ETHYLENE DIAMINE DIHYDROCHLORIDE [HSDB]
Common Name English
NSC-9849
Code English
N-NAPHTHYLETHYLENEDIAMINE DIHYDROCHLORIDE
Systematic Name English
ETHYLENEDIAMINE, N-1-NAPHTHYL-, DIHYDROCHLORIDE
Common Name English
1,2-ETHANEDIAMINE, N-1-NAPHTHALENYL-, DIHYDROCHLORIDE
Common Name English
BRATTON-MARSHALL REAGENT
Brand Name English
1,2-ETHANEDIAMINE, N1-1-NAPHTHALENYL-, HYDROCHLORIDE (1:2)
Systematic Name English
Code System Code Type Description
MERCK INDEX
M7761
Created by admin on Tue Oct 22 13:36:11 UTC 2019 , Edited by admin on Tue Oct 22 13:36:11 UTC 2019
PRIMARY Merck Index
HSDB
1465-25-4
Created by admin on Tue Oct 22 13:36:11 UTC 2019 , Edited by admin on Tue Oct 22 13:36:11 UTC 2019
PRIMARY
MESH
C008588
Created by admin on Tue Oct 22 13:36:11 UTC 2019 , Edited by admin on Tue Oct 22 13:36:11 UTC 2019
PRIMARY
CAS
1465-25-4
Created by admin on Tue Oct 22 13:36:11 UTC 2019 , Edited by admin on Tue Oct 22 13:36:11 UTC 2019
PRIMARY
ECHA (EC/EINECS)
215-981-2
Created by admin on Tue Oct 22 13:36:11 UTC 2019 , Edited by admin on Tue Oct 22 13:36:11 UTC 2019
PRIMARY
EPA CompTox
1465-25-4
Created by admin on Tue Oct 22 13:36:11 UTC 2019 , Edited by admin on Tue Oct 22 13:36:11 UTC 2019
PRIMARY
Related Record Type Details
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