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Details

Stereochemistry ABSOLUTE
Molecular Formula C29H30N4O7
Molecular Weight 546.5711
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TRYPTOQUIVALINE

SMILES

CC(C)[C@H](OC(C)=O)C1=NC2=CC=CC=C2C(=O)N1[C@@H]3C[C@@]4(OC3=O)[C@@H]5N(O)C(C)(C)C(=O)N5C6=C4C=CC=C6

InChI

InChIKey=CYNVLFGDEQQUPE-LDWWEUSWSA-N
InChI=1S/C29H30N4O7/c1-15(2)22(39-16(3)34)23-30-19-12-8-6-10-17(19)24(35)31(23)21-14-29(40-25(21)36)18-11-7-9-13-20(18)32-26(29)33(38)28(4,5)27(32)37/h6-13,15,21-22,26,38H,14H2,1-5H3/t21-,22+,26+,29+/m1/s1

HIDE SMILES / InChI

Molecular Formula C29H30N4O7
Molecular Weight 546.5711
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2.
2008 Oct 1
Chrysin blocks topotecan-induced apoptosis in Caco-2 cells in spite of inhibition of ABC-transporters.
2010 Aug 15
Substance Class Chemical
Created
by admin
on Tue Oct 22 19:34:03 UTC 2019
Edited
by admin
on Tue Oct 22 19:34:03 UTC 2019
Record UNII
CW5S8OP3VO
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TRYPTOQUIVALINE
Common Name English
SPIRO(FURAN-2(5H),9'-(9H)IMIDAZO(1,2-A)INDOLE)-3',5(2'H)-DIONE, 4-(2-(1-(ACETYLOXY)-2-METHYLPROPYL)-4-OXO-3(4H)-QUINAZOLINYL)-1',3,4,9'A-TETRAHYDRO-1'-HYDROXY-2',2'-DIMETHYL-, (9'S-(9'.ALPHA.(4S*(R*)),9'A.BETA.))-
Common Name English
SPIRO(FURAN-2(5H),9'-(9H)IMIDAZO(1,2-A)INDOLE)-3',5(2'H)-DIONE, 4-(2-((1S)-1-(ACETYLOXY)-2-METHYLPROPYL)-4-OXO-3(4H)-QUINAZOLINYL)-1',3,4,9'A-TETRAHYDRO-1'-HYDROXY-2',2'-DIMETHYL-, (2S,4R,9'AS)-
Common Name English
TRYPTOQUIVALINE C
Common Name English
FUMITREMORGIN C
Common Name English
TRYPTOQUIVALINE A
Common Name English
Code System Code Type Description
PUBCHEM
108075
Created by admin on Tue Oct 22 19:34:04 UTC 2019 , Edited by admin on Tue Oct 22 19:34:04 UTC 2019
PRIMARY
CAS
55387-45-6
Created by admin on Tue Oct 22 19:34:04 UTC 2019 , Edited by admin on Tue Oct 22 19:34:04 UTC 2019
PRIMARY
Related Record Type Details
TRANSPORTER -> INHIBITOR