U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Mon Oct 21 20:41:00 UTC 2019
Edited
by admin
on Mon Oct 21 20:41:00 UTC 2019
Protein Type TRANSPORTER
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
B46KUN2O9L
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MATE-2
Common Name English
MATE-2K
Common Name English
SLC47A2
Common Name English
HMATE-2K
Common Name English
SOLUTE CARRIER FAMILY 47 MEMBER 2
Common Name English
HMATE-2
Common Name English
MATE2
Common Name English
MULTIDRUG AND TOXIN EXTRUSION PROTEIN 2
Common Name English
MATE2-K
Common Name English
FLJ31196
Common Name English
Classification Tree Code System Code
UCSF-FDA TRANSPORTAL SLC47A2
Created by admin on Mon Oct 21 20:41:00 UTC 2019 , Edited by admin on Mon Oct 21 20:41:00 UTC 2019
Code System Code Type Description
WIKIPEDIA
SLC47A2
Created by admin on Mon Oct 21 20:41:00 UTC 2019 , Edited by admin on Mon Oct 21 20:41:00 UTC 2019
PRIMARY
UNIPROT
Q86VL8
Created by admin on Mon Oct 21 20:41:00 UTC 2019 , Edited by admin on Mon Oct 21 20:41:00 UTC 2019
PRIMARY
Related Record Type Details
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> METABOLIC ENZYME
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR
IC50
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
WEAK
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
IC50
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
Rifamycin is an inhibitor of renal transporters organic anion transporter (OAT) 3, multidrug and toxin extrusion (MATE) 1, and MATE2-K transporters in vitro, however, based on systemic concentrations of rifamycin observed after administration of the recommended dose, clinically relevant inhibition of these transporters in vivo is unlikely.
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL