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Details

Stereochemistry ABSOLUTE
Molecular Formula C21H20O12
Molecular Weight 464.3771
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HYPEROSIDE

SMILES

c1cc(c(cc1-c2c(c(=O)c3c(cc(cc3o2)O)O)O[C@@]4([H])[C@@]([H])([C@]([H])([C@]([H])([C@@]([H])(CO)O4)O)O)O)O)O

InChI

InChIKey=OVSQVDMCBVZWGM-DTGCRPNFSA-N
InChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15+,17+,18-,21+/m1/s1

HIDE SMILES / InChI

Molecular Formula C21H20O12
Molecular Weight 464.3771
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 5 / 5
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Inhibition of HIV infection by flavanoids.
1993 Oct
A new flavonol glycoside gallate ester from Acer okamotoanum and its inhibitory activity against human immunodeficiency virus-1 (HIV-1) integrase.
1998 Jan
A search for anti-viral properties in Panamanian medicinal plants. The effects on HIV and its essential enzymes.
1999 Jan
St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor.
2000 Jun 20
Herbal remedies of Solidago--correlation of phytochemical characteristics and antioxidative properties.
2003 Aug 8
Isolation and characterization of antioxidant phenolic compounds from the aerial parts of Hypericum hyssopifolium L. by activity-guided fractionation.
2003 Jul
[HPLC investigation of antioxidant components in Solidago herba].
2004
Depsides from the petals of Papaver rhoeas.
2004 Apr
Application of preparative high-speed counter-current chromatography for the separation of flavonoids from the leaves of Byrsonima crassa Niedenzu (IK).
2004 Apr 30
The protozoan Tetrahymena as a bioindicator to screen bioactive substances.
2004 Nov
Flavonoids and antiulcerogenic activity from Byrsonima crassa leaves extracts.
2005 Feb 10
Antioxidant activity of anthraquinones and flavonoids from flower of Reynoutria sachalinensis.
2005 Jan
3-O-beta-D-Galactopyranoside of quercetin as an active principle from high altitude Podophyllum hexandrum and evaluation of its radioprotective properties.
2005 Sep-Oct
Anti-HIV protease activity from rosa family plant extracts and rosamultin from Rosa rugosa.
2005 Spring
Mutagenic activity promoted by amentoflavone and methanolic extract of Byrsonima crassa Niedenzu.
2006 Aug 1
Binding interaction of quercetin-3-beta-galactoside and its synthetic derivatives with SARS-CoV 3CL(pro): structure-activity relationship studies reveal salient pharmacophore features.
2006 Dec 15
Constituents from the leaves of Phellodendron amurense and their antioxidant activity.
2006 Sep
[Studies on chemical constituentsfrom leaves of Acer truncatum].
2007 Aug
In silico prediction of pregnane X receptor activators by machine learning approaches.
2007 Jan
Mutagenic evaluation and chemical investigation of Byrsonima intermedia A. Juss. leaf extracts.
2007 Jun 13
Constituents and antiulcer effect of Alchornea glandulosa: activation of cell proliferation in gastric mucosa during the healing process.
2007 Mar
The mechanism of hyperoside protection of ECV-304 cells against tert-butyl hydroperoxide-induced injury.
2008
[Studies on chemical constituents from Davidia involucrata var. vilmoriniana].
2008 Apr
Deconjugation and degradation of flavonol glycosides by pig cecal microbiota characterized by Fluorescence in situ hybridization (FISH).
2008 Mar 26
Phytochemicals of apple peels: isolation, structure elucidation, and their antiproliferative and antioxidant activities.
2008 Nov 12
Effect of flavonoids from Exellodendron coriaceum (Chrysobalanaceae) on glucose-6-phosphatase.
2009 Dec
DOSY NMR applied to analysis of flavonoid glycosides from Bidens sulphurea.
2009 Dec
A new dihydrodibenzodioxinone from Hypericum x 'Hidcote'.
2009 Jun
The constituents and their bioactivities of Houttuynia cordata.
2009 Nov
Phenolic compounds in leaves of Alchornea triplinervia: anatomical localization, mutagenicity, and antibacterial activity.
2010 Aug
[Chemical constituents of Laggera pterodonta].
2010 Mar
Antioxidant and enzyme inhibition activities and chemical profiles of Polygonum sachalinensis F.Schmidt ex Maxim (Polygonaceae).
2010 Mar
Estrogenic/antiestrogenic activities of a Epimedium koreanum extract and its major components: in vitro and in vivo studies.
2012 Aug
Discovery of flavonoid derivatives as anti-HCV agents via pharmacophore search combining molecular docking strategy.
2012 Jun
Antiplasmodial activity of flavonol quercetin and its analogues in Plasmodium falciparum: evidence from clinical isolates in Bangladesh and standardized parasite clones.
2012 Jun
Patents

Patents

Substance Class Chemical
Created
by admin
on Sat Jun 26 06:16:23 UTC 2021
Edited
by admin
on Sat Jun 26 06:16:23 UTC 2021
Record UNII
8O1CR18L82
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HYPEROSIDE
USP-RS  
Common Name English
NSC-407304
Code English
HYPEROSIDE [USP-RS]
Common Name English
QUERCETIN 3-.BETA.-D-GALACTOPYRANOSIDE
Common Name English
QUERCETIN-3-O-GALACTOSIDE
Common Name English
HYPEROSID
Common Name English
QUERCETIN 3-O-.BETA.-D-GALACTOSIDE
Systematic Name English
HYPERIN
Common Name English
HYPEROSIDE (CONSTITUENT OF HAWTHORN LEAF WITH FLOWER) [DSC]
Common Name English
HYPEROSIDE (CONSTITUENT OF ST. JOHN'S WORT) [DSC]
Common Name English
2-(3,4-DIHYDROXYPHENYL)-3-(.BETA.-D-GALACTOPYRANOSYLOXY)-5,7-DIHYDROXY-4H-1-BENZOPYRAN-4-ONE
Common Name English
Classification Tree Code System Code
DSLD 1394 (Number of products:104)
Created by admin on Sat Jun 26 06:16:23 UTC 2021 , Edited by admin on Sat Jun 26 06:16:23 UTC 2021
DSLD 4101 (Number of products:1)
Created by admin on Sat Jun 26 06:16:23 UTC 2021 , Edited by admin on Sat Jun 26 06:16:23 UTC 2021
Code System Code Type Description
USP_CATALOG
1335202
Created by admin on Sat Jun 26 06:16:23 UTC 2021 , Edited by admin on Sat Jun 26 06:16:23 UTC 2021
PRIMARY USP-RS
FDA UNII
8O1CR18L82
Created by admin on Sat Jun 26 06:16:23 UTC 2021 , Edited by admin on Sat Jun 26 06:16:23 UTC 2021
PRIMARY
PUBCHEM
5281643
Created by admin on Sat Jun 26 06:16:23 UTC 2021 , Edited by admin on Sat Jun 26 06:16:23 UTC 2021
PRIMARY
ECHA (EC/EINECS)
207-580-6
Created by admin on Sat Jun 26 06:16:23 UTC 2021 , Edited by admin on Sat Jun 26 06:16:23 UTC 2021
PRIMARY
CAS
482-36-0
Created by admin on Sat Jun 26 06:16:23 UTC 2021 , Edited by admin on Sat Jun 26 06:16:23 UTC 2021
PRIMARY
MESH
C021304
Created by admin on Sat Jun 26 06:16:23 UTC 2021 , Edited by admin on Sat Jun 26 06:16:23 UTC 2021
PRIMARY
WIKIPEDIA
HYPEROSIDE
Created by admin on Sat Jun 26 06:16:23 UTC 2021 , Edited by admin on Sat Jun 26 06:16:23 UTC 2021
PRIMARY
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Secondary metabolite detected in developing cacao seeds.