U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Mon Oct 21 23:03:43 UTC 2019
Edited
by admin
on Mon Oct 21 23:03:43 UTC 2019
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
6FY6EI1X8R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
EMACTUZUMAB
INN   USAN   WHO-DD  
INN   USAN  
Official Name English
RO5509554
Code English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS CSF1R (COLONY STIMULATING FACTOR 1 RECEPTOR, CSF-1R, CSF-1-R, MACROPHAGE COLONYSTIMULATING FACTOR 1 RECEPTOR, C-FMS, FMS, CD115)), HUMANIZED MONOCLONAL ANTIBODY
Common Name English
RO5509554 (ANTI-CSF-R1)
Code English
RO-5509554
Code English
7I1955N5WX
Common Name English
EMACTUZUMAB [USAN]
Common Name English
EMACTUZUMAB [WHO-DD]
Common Name English
RG-7155
Code English
RG7155
Code English
IMMUNOGLOBULIN G1, ANTI-(HUMAN MACROPHAGE COLONY-STIMULATING FACTOR RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL LIGHT CHAIN, DIMER
Systematic Name English
EMACTUZUMAB [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Mon Oct 21 23:03:43 UTC 2019 , Edited by admin on Mon Oct 21 23:03:43 UTC 2019
FDA ORPHAN DRUG 431614
Created by admin on Mon Oct 21 23:03:43 UTC 2019 , Edited by admin on Mon Oct 21 23:03:43 UTC 2019
Code System Code Type Description
CAS
1448221-67-7
Created by admin on Mon Oct 21 23:03:43 UTC 2019 , Edited by admin on Mon Oct 21 23:03:43 UTC 2019
PRIMARY
ChEMBL
CHEMBL2109324
Created by admin on Mon Oct 21 23:03:43 UTC 2019 , Edited by admin on Mon Oct 21 23:03:43 UTC 2019
PRIMARY
INN
9951
Created by admin on Mon Oct 21 23:03:43 UTC 2019 , Edited by admin on Mon Oct 21 23:03:43 UTC 2019
PRIMARY
EVMPD
SUB177212
Created by admin on Mon Oct 21 23:03:43 UTC 2019 , Edited by admin on Mon Oct 21 23:03:43 UTC 2019
PRIMARY
ChEMBL
CHEMBL3545370
Created by admin on Mon Oct 21 23:03:43 UTC 2019 , Edited by admin on Mon Oct 21 23:03:43 UTC 2019
PRIMARY
NCI_THESAURUS
C125548
Created by admin on Mon Oct 21 23:03:43 UTC 2019 , Edited by admin on Mon Oct 21 23:03:43 UTC 2019
PRIMARY
From To
1_22 1_95
1_143 1_199
1_260 1_320
1_366 1_424
2_22 2_95
2_143 2_199
2_260 2_320
2_366 2_424
3_23 3_88
3_133 3_193
4_23 4_88
4_133 4_193
1_219 3_213
2_219 4_213
1_225 2_225
1_228 2_228
Glycosylation Link Type Site
N 1_296
N 2_296
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED) CHEMICAL