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Details

Stereochemistry ACHIRAL
Molecular Formula C7H8N4S
Molecular Weight 180.2316
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of NICOTHIAZONE

SMILES

c1cc(cnc1)/C(/[H])=N/NC(=N)S

InChI

InChIKey=ABWLRVJYVVQTGQ-BJMVGYQFSA-N
InChI=1S/C7H8N4S/c8-7(12)11-10-5-6-2-1-3-9-4-6/h1-5H,(H3,8,11,12)/b10-5+

HIDE SMILES / InChI

Molecular Formula C7H8N4S
Molecular Weight 180.2316
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Nicothiazone (nicotinaldehyde thiosemicarbazone), an antituberculosis drug, was apparently responsible for inducing vacuoles in the corneal epithelium and thus caused discomfort and photophobia from corneal disturbance.

Approval Year

Conditions

Conditions

PubMed

PubMed

TitleDatePubMed
Inactivation of herpes simplex virus by thiosemicarbazones and certain cations.
1974 Apr

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Jun 26 16:39:23 UTC 2021
Edited
by admin
on Sat Jun 26 16:39:23 UTC 2021
Record UNII
2MR9VJF32M
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NICOTHIAZONE
INN  
INN  
Official Name English
NSC-730
Code English
NICOTHIAZONE [INN]
Common Name English
NICOTINALDEHYDE THIOSEMICARBAZONE
Systematic Name English
HYDRAZINECARBOTHIOAMIDE, 2-(3-PYRIDINYLMETHYLENE)-
Systematic Name English
SRI-286
Code English
Classification Tree Code System Code
NCI_THESAURUS C280
Created by admin on Sat Jun 26 16:39:23 UTC 2021 , Edited by admin on Sat Jun 26 16:39:23 UTC 2021
Code System Code Type Description
EPA CompTox
555-90-8
Created by admin on Sat Jun 26 16:39:23 UTC 2021 , Edited by admin on Sat Jun 26 16:39:23 UTC 2021
PRIMARY
FDA UNII
2MR9VJF32M
Created by admin on Sat Jun 26 16:39:23 UTC 2021 , Edited by admin on Sat Jun 26 16:39:23 UTC 2021
PRIMARY
INN
462
Created by admin on Sat Jun 26 16:39:23 UTC 2021 , Edited by admin on Sat Jun 26 16:39:23 UTC 2021
PRIMARY
CAS
555-90-8
Created by admin on Sat Jun 26 16:39:23 UTC 2021 , Edited by admin on Sat Jun 26 16:39:23 UTC 2021
PRIMARY
EVMPD
SUB09245MIG
Created by admin on Sat Jun 26 16:39:23 UTC 2021 , Edited by admin on Sat Jun 26 16:39:23 UTC 2021
PRIMARY
ECHA (EC/EINECS)
209-108-4
Created by admin on Sat Jun 26 16:39:23 UTC 2021 , Edited by admin on Sat Jun 26 16:39:23 UTC 2021
PRIMARY
PUBCHEM
6474573
Created by admin on Sat Jun 26 16:39:23 UTC 2021 , Edited by admin on Sat Jun 26 16:39:23 UTC 2021
PRIMARY
ChEMBL
CHEMBL224265
Created by admin on Sat Jun 26 16:39:23 UTC 2021 , Edited by admin on Sat Jun 26 16:39:23 UTC 2021
PRIMARY
NCI_THESAURUS
C82928
Created by admin on Sat Jun 26 16:39:23 UTC 2021 , Edited by admin on Sat Jun 26 16:39:23 UTC 2021
PRIMARY
Related Record Type Details
ACTIVE MOIETY