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Details

Stereochemistry ABSOLUTE
Molecular Formula C30H50O2
Molecular Weight 442.7168
Optical Activity UNSPECIFIED
Defined Stereocenters 8 / 8
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of URSADIOL

SMILES

CC1(C)CC[C@]2(C)[C@@H](O)C[C@]3(C)C(CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)=C2C1

InChI

InChIKey=RTLXJEJRLWILSU-GWNGJUQLSA-N
InChI=1S/C30H50O2/c1-25(2)15-16-27(5)20(17-25)19-9-10-22-28(6)13-12-23(31)26(3,4)21(28)11-14-29(22,7)30(19,8)18-24(27)32/h21-24,31-32H,9-18H2,1-8H3/t21-,22+,23-,24-,27-,28-,29+,30+/m0/s1

HIDE SMILES / InChI

Description

Coflodiol, also known as ursadiol, is a triterpenoid, isolated from the non-saponifiable lipid fraction of the flower extract of chrysanthemum (Chrysanthemum morifolium). This compound possesses minimal antitubercular activity against Mycobacterium tuberculosis.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
PubMed

PubMed

TitleDatePubMed
Antitubercular activity of triterpenoids from Asteraceae flowers.
2005 Jan

Sample Use Guides

In Vitro Use Guide
Antitubercular activity of compounds in DMSO was determined against Mycobacterium tuberculosis H37Rv (ATCC 27294) in Middlebrook 7H12 medium. Minimum Inhibitory Concentrations for Coflodiol was >64 ug/mL
Name Type Language
URSADIOL
Common Name English
OLEAN-13(18)-ENE-3,16-DIOL, (3.BETA.,16.BETA.)-
Common Name English
COFLODIOL
Common Name English
Code System Code Type Description
EPA CompTox
37384-13-7
Created by admin on Tue Oct 22 13:48:09 UTC 2019 , Edited by admin on Tue Oct 22 13:48:09 UTC 2019
PRIMARY
PUBCHEM
5273648
Created by admin on Tue Oct 22 13:48:09 UTC 2019 , Edited by admin on Tue Oct 22 13:48:09 UTC 2019
PRIMARY
CAS
37384-13-7
Created by admin on Tue Oct 22 13:48:09 UTC 2019 , Edited by admin on Tue Oct 22 13:48:09 UTC 2019
PRIMARY